Rumored Buzz on Conolidine alkaloid for chronic pain
Most lately, it has been identified that conolidine and the above derivatives act to the atypical chemokine receptor three (ACKR3. Expressed in comparable regions as classical opioid receptors, it binds to your big selection of endogenous opioids. Unlike most opioid receptors, this receptor acts for a scavenger and doesn't activate a 2nd messenger